For those that don't know, Genesis is a Framework by Studiopress with a default theme you plug into Wordpress. Its not free, you have to buy it, but unlike free themes and many premium; because its a framework you have lots of options.
With click of a button you can change your screen to have header and content, just content, header, 1 sidebar and content, header and 2 sidebars and content, etc... You get the idea, you can change your layout to a number of configuration. But it doesn't stop there. Genesis also contains an SEO element; it allows a number of places to place widgets and all this from the GUI; no code required.
Add a little CSS to place items more precise and you soon have a very professional looking webpage. In my testing; in 1 hours I went from a drap site to a quite semi-pro looking site; check out http://www.techno-info.co.uk for an example.
Also; keep your eyes peeled for up and coming review if interested.